Zetsu (ゼツ, Zetsu) could refer to:
- Black Zetsu: The artificial human created when Madara Uchiha injected his will into White Zetsu.
- Spiral Zetsu: An clone of White Zetsu with a spiral-shaped head.
- White Zetsu: The artificial human, created by Madara, using Hashirama's living clone and the Demonic Statue of the Outer Path.
- White Zetsu Army: The army of 100,000 White Zetsu clones that act as Akatsuki's main forces in the Fourth Shinobi World War.