RikudoSasuke wrote:
well if were talking current sasuke ,izanami wouldnt work since he's conquered his inner demons.also im very sure only senjutsu is effective against limbo so the totsuka wouldnt affect it.plus itachi cant even see limbo.itachi is useless except for his highest level attacks i.e.totsuka ,tsukuyomi ,izanami and possibly izanagi(maybe).madara can possibly negate totsuka with yin-yang or if not sasuke and madara are fast enough to just dodge it not forgetting sasuke can teleport out of the way at any time.tsukuyomi is probably nothing to sasuke because of his ems+rinnegan and the fact that he's itachis brother and has been in tsukuyomi before.im not sure how madara would react to tsukuyomi though but possibly being an uchiha and having an ems-turned-rinnegan helps his chances.izanagi would only kill time and izanami has been discussed.so iachi isnt really a big player in this match
You are really unplaying the Totsuka Blade, doesn't matter what the defence is, it pierces everything, it's a one hit kill on everything. Orochimaru never found it in his life since it's a spirit weapon, it's unique to Itachi so none but those he showed it to knew of it, no one but Sasuke survived an encounter with it and that's 'cause Itachi never meant to kill him.
Madara would not even know of Izanami since he was the first to awaken the Mangekyō and the one who created it also had a Mangekyō, he would have been dead by that time. He did use Izanagi so he might feel a resemblance in the effect. Besides Izanami was created to stop people who were dead set on altering reality. Infinite Tsukuyomi is altering reality to an extent, so Izanami would take hold.
Itachi has the Yata Mirror, a shield that changes itself to deflect or block an attack. It would just adapt to the attacks thrown at it. Not saying he's all powerful but Itachi has more of a chance on his own than Sasuke does alone