"The Snake and…" (蛇と…, Hebi to…) is chapter 344 of the original Naruto manga.
Sasuke tells Orochimaru that there is nothing else for him to learn as he is already stronger than Orochimaru. Moreover, he has no intention of giving his body and the Sharingan to someone like Orochimaru, who constantly tries to escape death. As Sasuke tries to finish him off, Orochimaru abandons his body, revealing his true form as a large, white snake. He attacks Sasuke, intending to take his body by force. Sasuke responds by activating level two of his cursed seal.