"The Sad Conclusion" (悲しき決着, Kanashiki Ketchaku) is chapter 296 of the original Naruto manga.
Kabuto, Sakura, and Yamato get away from the struggling Naruto. Kabuto, seeing his four-tailed transformation, remarks that Naruto has allowed himself to become a monster to find Sasuke. Distraught over what Naruto is putting himself through, Sakura approaches him to try and calm him down but Naruto, no longer able to distinguish between friend and foe, attacks her. Yamato suppresses the Nine-Tailed Demon Fox's influence over Naruto while Kabuto tends to Sakura, thanks for eliminating Sasori. Meanwhile, Orochimaru collapses from the strain put on his body by fighting Naruto. He is approached by Sai, who asks for a chance to speak with him on behalf of Danzō.