"The Child of the Prophecy!!" (予言の子!!, Yogen no Ko!!) is chapter 376 of the original Naruto manga.
Having entered Sage Mode, Jiraiya faces Pain in battle with the help of Ma and Pa. They ask why he would need their help, to which he responds he must kill a former pupil. Finding this significant, Ma and Pa locate the chameleon Pain is hiding in and force him to show himself. Seeing his Rinnegan, they reflect on a prophecy that was made about Jiraiya. Jiraiya would have a student with the power to save or destroy the world. Seeing that Pain has taken the path to the world's destruction, they prepare for battle. Pain also prepares by summoning two bodies.