|This is the article on episode 450 of Naruto: Shippūden. For episode 258 of Naruto: Shippūden, head to Rivals.|
|Previous||"The Shinobi Unite"|
|Episode||Naruto: Shippūden #450 (Watch Online)|
|Next||"Birth and Death"|
|Arc||Jiraiya Shinobi Handbook: The Tale of Naruto the Hero|
|Manga||Naruto Chapter #678|
|Japanese||February 25, 2016|
Sasuke agrees to return to Konoha, but denies being comrades with the others again, intent on changing how the village works. Naruto and Sasuke fight on Orochimaru's old hideout, arguing about the past, Sasuke accusing Naruto of advancing too fast, leaving him behind. After fighting it out, Naruto and Sasuke make up, and return to Konoha. Tsunade wakes up from having fallen asleep after reading Jiraiya's novel when Dan calls her. In the real world, Tsunade mumbles in her sleep, as she and countless others are trapped in the Infinite Tsukuyomi.
- Sasuke is shown using his Eternal Mangekyō Sharingan version Susanoo, despite possessing the regular Mangekyō Sharingan.
- The moment where Sasuke tries to save Shiro, he is stopped by a ninja that resemble Obito Uchiha both in appearance and voice.
|Fifth Hokage: Tsunade||Masako Katsuki||勝生真沙子||Katsuki Masako|
|Jiraiya||Hochu Otsuka||大塚 芳忠||Ōtsuka Hōchū|
|Dan Katō||Takuma Suzuki||鈴木 琢磨||Suzuki Takuma|
|Naruto Uzumaki||Junko Takeuchi||竹内 順子||Takeuchi Junko|
|Sasuke Uchiha||Noriaki Sugiyama||杉山 紀彰||Sugiyama Noriaki|
|Kurama||Tessho Genda||玄田 哲章||Genda Tesshō|
|Minato Namikaze||Toshiyuki Morikawa||森川 智之||Morikawa Toshiyuki|
|Fugaku Uchiha||Kenji Hamada||浜田 賢二||Hamada Kenji|
|Uchiha's shinobi||Kosuke Goto||後藤 光祐||Gotō Kōsuke|