Reality…!! (現実…!!, Genjitsu…!!) is chapter 387 of the Naruto manga.
Itachi insists that Sasuke, with a normal Sharingan, cannot defeat his Mangekyō Sharingan. Sasuke merely repeats his promise to kill Itachi and attacks. The two exchange blows and have a contest of projectile weapons, but Itachi is ultimately able to gain the upper-hand. He pins Sasuke to the wall and plucks out one of his eyes.