Chakra is kneaded within the body and then changed into special chemical substances. It is then ejected through the mouth! When this substance comes in contact with the air outside the body, it instantly changes and is transformed into a mist of deadly poison...!! As this technique combines ninjutsu, chemistry, and medical knowledge, using it requires fine chakra control and advanced ability in medical ninjutsu.
The poison's ability to kill is tremendous. Just breathing in a small amount will mean the end of one's life, right there and then.
The Poison Mist used by Ibuse differs from that used by Shizune. Rather than kill those that inhale it, Ibuse's causes victims to become paralyzed after only a few seconds, allowing Hanzō to attack them at his leisure with his kusarigama. Ibuse must first generate and store the poison within his body for five minutes before he can use it.