|Jūgo's Clan's Kekkei Genkai|
|Anime||Naruto Shippūden Episode #117|
|Game||Naruto Shippūden: Dragon Blade Chronicles|
|Appears in||Anime, Manga, Game|
Members of Jūgo's clan have unique enzymes which allow them to passively absorb and effectively make use of natural energy, with or without training in senjutsu. However, due to the constant intake of natural energy, they are prone to mental instability, sporadically feeling sudden and uncontrollable urges to kill. Though Kabuto, who genetically altered his DNA to obtain this trait, does not seem to suffer from this side-effect. The wielder's body can also secrete special fluids which, through means of Senjutsu chakra, allow them to transform parts of their bodies. While varied by appearance and function from user to user and even from use to use, the affected parts of their skin change colour (the hair colour also may change) and if the transformation occurs in the eyes, they change colour as well. Seemingly, the risk of petrification from the imbalance of natural energy, appears to be non-existent.
After Jūgo massacred an entire village during one of his rages, he secluded himself, living in caves, until he was approached by Kimimaro, who told him Orochimaru could help him with his urges. Jūgo went to Orochimaru voluntarily, and allowed him to research his transformations. More interested in the source of the transformation than in curbing the killing urges, Orochimaru experimented with Jūgo's body fluids, developing an enzyme that can trigger similar changes in other, suitable hosts, through cursed seals, which Orochimaru determined to be ten percent of the population, all others dying after having the cursed seal applied. However, their transformations are limited to fixed forms, able only to transform into a specific form back and forth. His investigations on the source of their power also led him to the discovery of Ryūchi Cave.
After Sasuke absorbed Orochimaru, Kabuto Yakushi found himself without purpose, and following Orochimaru's belief of adding to himself to find his true self, injected himself with the biological material of the subjects of many of Orochimaru's experiments, including Jūgo. Doing his all to emulate his master, Kabuto went to the Ryūchi Cave, and the ability to absorb natural energy passively aided him in training senjutsu under the White Snake Sage.