This clan is an unknown family, which originated from an unknown area. The members of this clan possess the innate ability to absorb natural energy from their surroundings due to their unique bodies, however, the adverse effects of this energy results in sudden and uncontrollable surges of madness, causing them to sporadically go berserk. Their unique bodies also secrete special fluids that allow them to undergo various drastic physical alterations.
The only known member is Jūgo, who was said to have voluntarily gone to Orochimaru in the hopes that he could be cured of his fits of rage. According to Kabuto Yakushi, Orochimaru's subsequent investigations and experimentation allowed him to discover the origin of the clan's power at the Ryūchi Cave, where he and later Kabuto learned Sage Mode.