Sai is able to make use of the clone for missions involving surprise attacks, infiltration, and assassinations. However, experienced ninja such as Orochimaru are able to see through this technique. Sai and his clones also have the ability to stay mentally in contact with each other. If Sai is rendered unconscious, his ink clones are dispersed.
The Eight-Tails's ink allows Killer B to make replicas of himself. These replicas are also able to form partial transformations of the Eight-Tails.