"Hate Among the Uchihas: The Last of the Clan!" (愚かなる弟よ 恨め、憎め!, Orokanaru Otōto yo Urame, Nikume!) is episode 85 of the original Naruto anime.
Kisame's would-be fatal attack is blocked by Gama, and Jiraiya tells the two Akatsuki members that cheap tricks like putting a young woman under genjutsu would never work on him. Standing to his feet again, Sasuke tells the Sannin to stay out of his own fight, but is easily beaten down by Itachi who tells his brother that he was still too weak and he still hasn't mustered enough hatred. Deeming it necessary to make him stronger, Itachi activated Tsukuyomi and forced Sasuke to relive his parent's and other clan member's death. As Naruto rushes forward to aid his comrade, Kisame prepared to attack him, but Jiraiya uses the Summoning: Toad Mouth Bind technique to stop the two Akatsuki members. The entire area became the oesophagus of the Mountain Toad, with Kisame's foot and sword already starting to be absorbed as Jiraiya began explaining his technique. Sasuke was absorbed into the wall, thus being saved from Itachi. Itachi instructed Kisame to come with him, knowing that the only way they could survive this technique was to escape. Itachi was forced to use Amaterasu to burn a hole in the toad's oesophagus, allowing them to escape. Jiraiya later sealed away the flames. As Jiraiya and Naruto were checking on Sasuke, Guy suddenly appeared out of nowhere and kicked the Sannin in the face with his Dynamic Entry. He had thought that Naruto and Jiraiya were Itachi and Kisame after using the reflection from his forehead protector to check what was ahead. He had seen two figures in the dull reflection, so he had automatically assumed that Itachi and Kisame were still there. Naruto thought back on Sasuke's defeat at Itachi's hands. He resolved to go after Itachi and Kisame for doing that to Sasuke, but was quickly shot down by a more realistic Jiraiya, who knew that Naruto was nowhere near Itachi and Kisame's league. Naruto learned about Kakashi having been injured, and Guy talked about needing a medical specialist to help, not only with Kakashi and Sasuke, but with Lee as well. Jiraiya told Guy the person he needed was who they were searching for: the healing specialist, queen of slugs and elixirs, legendary Sannin, and failed gambler, Tsunade.