Hashirama Senju (千手柱間, Senju Hashirama) is chapter 620 of the Naruto manga.
As Sasuke boldly declares that Hashirama's response would decide whether or not he should take revenge on Konohagakure, an enraged Tobirama states he would not allow it as he prepares to fight Sasuke. However, in a fierce exchange of silent wills that sends those around them into near-frenzied panic while the Naka Shrine quakes from the energy from their stand off, Tobirama finally stands down at Hashirama's order with Hiruzen breathing a sigh of relief and Minato marvelled. Praising Itachi to be a better shinobi than himself, Hashirama agrees to answer though it will be a long one. When he tells takes the First Hokage to make it abridged, Orochimaru reveals the war occurring outside the village with Madara leading the attack. While Hiruzen pleas Orochimaru to let them go and aid their people, Minato and Tobirama sense the situation to confirm it, with the former glad that his son was able to work with Kurama. Even after Orochimaru refuses to have them leave and considers having them ironically destroy Konoha on Sasuke's choice, Tobirama ignores his summoner's threat as he was about to go to the battlefield. However, thanks to now acquiring Hashirama's genetic material, the binding of the Impure World Reincarnation had become more powerful with only Hashirama breaking free of the additional restraint. Allaying the Sannin's fears, Hashirama tells Orchimaru that he intends to first free Sasuke from the darkness surrounded him as he casually takes a seat on the ground and begins the retelling of the story of his confrontation with Madara at the Valley of the End and the history of the Senju and Uchiha.
In the original publication, when Sasuke deactivates his Mangekyō Sharingan, it is his own, regular Mangekyō Sharingan, without Itachi's Mangekyō on top of it. In the tankōbon release, Itachi's Mangekyō is added, resulting in Sasuke's Eternal Mangekyō Sharingan.