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Since like Mito Uzumaki is both Kushina Uzumaki and Tsunade grandmother, Doesn't that mean they're like step sisters or cousins?
Kushina and Tsunade
Isn't Mito just Kushina's predescessor (forgive the spelling) for being the ninetail's jinchuriiki? the manga also states that she was also from the land of whirpools. Was it mentioned that Mito was also part of the UZUMAKI clan from the land of whirpools? --- ShuHanShi
Mito Uzumaki is not the Grandmother of Kushina Uzumaki, they are just from the same clan, though this would suggest that they are related (most liekly by blood due to the special chakras they both have) it would also mean that in terms of Tsunade being related (distantly) to Kushina this is possible (as with naruto) as the manga has stated that the 1st was married to Mito (but untill the manga explicitly says that Mito is Lady Tsunade's Grandmother we can only assume so) -- Adott