"Cursed Seal Counterattack" (呪印の逆襲, Juin no Gyakushū) is episode 109 of the Naruto: Shippūden anime.
The Orochimaru Search Team is unable to locate Naruto or Guren by the lake, worrying Yūkimaru. He goes off with Sai as Kakashi, Shino and Yamato prepare to deal with the Three-Tailed Turtle, whom they have just awoken. Shizune, Ino, Sakura and Hinata stand behind them and erect the Four-Corner Sealing Barrier in an attempt to seal away the tailed beast once more. Team Guren, with enhanced strength due to their cursed seals, make quick work of Lee, Tenten, Kiba and Akamaru and move on to deal with Sai. Sai ends up losing the fight, although he is able to use his Super Beast Imitating Drawing technique to transmit a warning to Kakashi.
After defeating Sai and retrieving Yūkimaru, the team brings him to Rinji and state that they have no need to follow him anymore and that they are going off on their own. However, they soon succumb to the after effects of the cursed seal and are forced to beg Rinji for Kabuto's pills, which would counteract those effects. After pledging their loyalty to Orochimaru, they head off to deal with the Konoha shinobi as Rinji pressures Yūkimaru into using his Three-Tails Chakra: Release once more.
Sensing their enemies, Yamato uses his Wood Release: World of Trees Wall to protect the sealing team while simultaneously dealing with Kihō, who launches a Smoke Dragon towards him, engulfing him in smoke. Kakashi deals with Kigiri, who tricks him using a Smoke Clone and then creates multiple smoke clones to aid in their fight; Shino has his bugs attack Nurari, only for Nurari to slip the bugs off and use his Viscous Water Mass attack against Shino. Elsewhere, as Akamaru manages to locate Sai, Naruto and Guren regain consciousness and realise that they have escaped from the belly of the beast. However, they spot a beam of chakra hitting the sky and realise that Yūkimaru is using his power once more.