Even without being a jinchuriki of any kind, Hashirama defeated Madara Uchiha and the Nine-Tails simultaneously... an unbelievably staggering feat, especially after watching Madara toy with five kage at once and understanding the power of the Kyuubi.
So I ask: if Hashirama were the Juubi Jinchuriki, could he be defeated??
Team Shinobi - Itachi, Jiraiya, Gaara, Tsunade, A, Might Gai, Konan, Onoki, Tobirama, Toneri, Hiruzen Sarutobi, and single-Sharingan Kakashi.
VS.
Ten-Tails Jinchuriki Hashirama Senju.